Journal: Acta biomaterialia
Article Title: The bio in the ink: cartilage regeneration with bioprintable hydrogels and articular cartilage-derived progenitor cells
doi: 10.1016/j.actbio.2017.08.005
Figure Lengend Snippet: Proof-of-concept of bioprinting anatomical structures. (A) A CAD model of a femur condyle is obtained (highlighted in blue) and (B) used to generate the G-code and the path of the dual printing system (showing in blue the path for the supporting material and in green that of the bioink). (C, E) The top part of the femur condyle is printed together with the supporting hydrogel, (D,F) that can be then removed leaving only the bioink(stainedinblue).(G)A model of the lower part of the joint and the under lying bone was produced using a DLP 3D printer and (H)the condyle structure was printed directly on top of it, as a proof-of-concept test to replace the missing an atomical part, via co-extrusion of the supporting sacrificial poloxamer and gelMA bioink. (I) This allows accurate printing of the shape both in presence of the supporting material and (J) after its removal. Scale bar is 5 mm. (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.)
Article Snippet: The proximal part was converted to and STL file and the model was eventually printed with a digital light projection 3D printer (Ember, Autodesk, USA) using a proprietary PR48 resin (Autodesk).
Techniques: Produced